检索范围:
排序: 展示方式:
Mouth the mirror of lungs: where does the connection lie?
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 405-409 doi: 10.1007/s11684-016-0476-5
Periodontitis is the chronic destructive disease of the periodontium (Gums) caused by host bacterial interactions. The effect of such host bacterial interactions in oral cavity also evokes a systemic response. Numerous studies have found common mechanisms of destruction for periodontal diseases and other chronic diseases like diabetes mellitus, atherosclerosis, respiratory diseases, and adverse pregnancy outcomes. Oral colonization by respiratory pathogens appears to be a risk factor for development of respiratory diseases and oral interventions aimed at reducing oral bacterial count have resulted in reduced incidence of these reparatory illness. This reflects the importance of oral hygiene among patients with respiratory illness. This review highlights the association between periodontal diseases and respiratory diseases.
关键词: periodontitis respiratory diseases acute pneumonia COPD
张祝琴,刘德培
《中国工程科学》 2017年 第19卷 第2期 页码 112-116 doi: 10.15302/J-SSCAE-2017.02.019
重大慢性非传染性疾病包括心脑血管疾病、癌症、呼吸系统疾病、糖尿病等,其流行给全球居民健康造成了重大威胁。为进一步对慢性病进行有效预防控制,促进健康、推动经济和社会发展,2014年中国工程院立项并开展了“重大慢性非传染性疾病防治的国际对比研究”项目,对国内外慢性病预防控制情况以及可供我们借鉴的经验进行了详细分析。本文从慢性病发病概况入手,分析了各种疾病的预防控制措施,并对不同国家的慢性病预防控制体系进行比较,凝练有益经验和方法,提出了增强我国慢性病预防控制的措施和建议。
null
《医学前沿(英文)》 2018年 第12卷 第2期 页码 189-195 doi: 10.1007/s11684-017-0533-8
Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverse respiratory events in the post anesthesia care unit (PACU). Results indicated that only 11.4% of the patients were considered at a high risk of OSAS. Age and body mass index are the key factors for the risk of OSAS prevalence in China and also gender specific. Furthermore, the incidence of adverse respiratory events in the PACU was higher in patients with high risk of OSAS than others (6.8% vs. 0.9%, <0.001). They also stayed longer than others in the PACU (95±28 min vs. 62±19 min, <0.001). Age, high risk for OSAS, and smoking were independent risk factors for the occurrence of adverse respiratory events in the PACU. The BQ may be adopted as a screening tool for anesthesiologists in China to identify patients who are at high risk of OSAS and determine the potential risk of developing postoperative respiratory complications in the PACU.
关键词: obstructive sleep apnea Berlin Questionnaire Chinese surgical patients adverse respiratory event
《医学前沿(英文)》 doi: 10.1007/s11684-023-1011-0
关键词: Paxlovid hemodialysis SARS-CoV-2 viral load chest CT scan
Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns
null
《医学前沿(英文)》 2016年 第10卷 第2期 页码 111-119 doi: 10.1007/s11684-016-0446-y
The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 brought back memories of the occurrence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002. More than 1500 MERS-CoV cases were recorded in 42 months with a case fatality rate (CFR) of 40%. Meanwhile, 8000 cases of SARS-CoV were confirmed in six months with a CFR of 10%. The clinical presentation of MERS-CoV ranges from mild and non-specific presentation to progressive and severe pneumonia. No predictive signs or symptoms exist to differentiate MERS-CoV from community-acquired pneumonia in hospitalized patients. An apparent heterogeneity was observed in transmission. Most MERS-CoV cases were secondary to large outbreaks in healthcare settings. These cases were secondary to community-acquired cases, which may also cause family outbreaks. Travel-associated MERS infection remains low. However, the virus exhibited a clear tendency to cause large outbreaks outside the Arabian Peninsula as exemplified by the outbreak in the Republic of Korea. In this review, we summarize the current knowledge about MERS-CoV and highlight travel-related issues.
Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish
《医学前沿(英文)》 2019年 第13卷 第1期 页码 126-130 doi: 10.1007/s11684-017-0603-y
关键词: Middle East respiratory syndrome coronavirus MERS-CoV pregnancy pediatrics
Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary
null
《医学前沿(英文)》 2012年 第6卷 第3期 页码 296-301 doi: 10.1007/s11684-012-0219-1
Despite the technique of cardiopulmonary bypass (CPB) improved the development of modern cardiac surgery, many factors during CPB have been reported to induce acute respiratory distress syndrome (ARDS). The present study was to investigate which pro-inflammatory factors involved in the early phase of ARDS. Ten patients underwent valve replacement surgery with or without ARDS were enrolled for analysis of pulmonary function and inflammatory factors release including white blood cell (WBC), neutrophils, CD11b, CD18, interleukin (IL)-8 and tumor necrosis factor-α (TNF-α). The results demonstrated that the ratio of arterial oxygen tension/fraction of inspire oxygen (PaO2/FiO2) was greatly reduced in ARDS patients, but only the release of TNF-α was significantly increased, which was reversely correlated to the values of PaO2/FiO2. Also, the count of neutrophils adhesive to pulmonary endothelial cells was significantly increased in ARDS patients. Therefore, we concluded that TNF-α was quickly up-regulated and involved in the pathogenesis of CPB-induced ARDS via guiding primed neutrophils to pulmonary interstitium.
关键词: tumor necrosis factor-α cardiopulmonary bypass inflammation acute respiratory distress syndrome
Middle East respiratory syndrome coronavirus: a comprehensive review
null
《医学前沿(英文)》 2016年 第10卷 第2期 页码 120-136 doi: 10.1007/s11684-016-0430-6
The Middle East respiratory syndrome coronavirus was first identified in 2012 and has since then remained uncontrolled. Cases have been mostly reported in the Middle East, however travel-associated cases and outbreaks have also occurred. Nosocomial and zoonotic transmission of the virus appear to be the most important routes. The infection is severe and highly fatal thus necessitating rapid and efficacious interventions. Here, we performed a comprehensive review of published literature and summarized the epidemiology of the virus. In addition, we summarized the virological aspects of the infection and reviewed the animal models used as well as vaccination and antiviral tested against it.
关键词: MERS coronavirus review
Laparoscopic treatment of liver diseases in children
Jia Wei, Jiexiong Feng
《医学前沿(英文)》 2011年 第5卷 第4期 页码 388-394 doi: 10.1007/s11684-011-0165-3
Prevalence of cardiovascular diseases in China
Jun-Jie XIAO MD, Yi-Han CHEN MD, PhD,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 16-20 doi: 10.1007/s11684-010-0007-8
关键词: cardiovascular diseases prevalence China risk factors prevention
null
《医学前沿(英文)》 2013年 第7卷 第3期 页码 389-394 doi: 10.1007/s11684-013-0281-3
Despite the current acceleration and increasing leadership of Chinese genetics research, genetics and its clinical application have largely been imported to China from the Occident. Neither genetics nor the scientific reductionism underpinning its clinical application is integral to the traditional Chinese worldview. Given that disease concepts and their incumbent diagnoses are historically derived and culturally meaningful, we hypothesize that the cultural expectations of genetic diagnoses and medical genetics practice differ between the Occident and China. Specifically, we suggest that an undiagnosed diseases program in China will differ from the recently established Undiagnosed Diseases Program at the United States National Institutes of Health; a culturally sensitive concept will integrate traditional Chinese understanding of disease with the scientific reductionism of Occidental medicine.
关键词: genetics cultural differences undiagnosed diseases program
Diagnosis and therapy of lacrimal system diseases by micro lacrimal endoscope
Nan XIANG, Weikun HU, Jing YUAN, Guigang LI, Haixia LIU
《医学前沿(英文)》 2009年 第3卷 第1期 页码 113-117 doi: 10.1007/s11684-009-0001-1
Responses to emerging and re-emerging infectious diseases: One world, One health
null
《医学前沿(英文)》 2018年 第12卷 第1期 页码 1-2 doi: 10.1007/s11684-018-0619-y
Mengmeng ZHAO,Juanjuan QIAN,Jiexiong XIE,Tiantian CUI,Songling FENG,Guoqiang WANG,Ruining WANG,Guihong ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 153-160 doi: 10.15302/J-FASE-2016097
Circulating microRNAs in cardiovascular diseases: from biomarkers to therapeutic targets
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 404-418 doi: 10.1007/s11684-014-0379-2
microRNAs (miRNAs) are a class of conserved, short, non-coding RNAs that have important and potent capacities to regulate gene expression at the posttranscriptional level. In the past several years, the aberrant expressions of miRNAs in the cardiovascular system have been widely reported, and the crucial roles of some special miRNAs in heart development and pathophysiology of various cardiovascular diseases have been gradually recognized. Recently, it was discovered that miRNAs are presented in peripheral circulation abundantly and stably. This has raised the possibility of using circulating miRNAs as biomarkers for diseases. Furthermore, some studies demonstrated that circulating miRNAs may serve as novel extracellular communicators of cell-cell communication. These discoveries not only reveal the functions of circulating miRNAs in cardiovascular system but also inform the development of miRNAs therapeutic strategies. In this review, we discuss the potential roles of circulating miRNAs in a variety of cardiovascular diseases from biomarkers to therapeutic targets to clearly understand the roles of circulating miRNAs in cardiovascular system.
关键词: microRNA cardiovascular disease biomarkers therapeutic target
标题 作者 时间 类型 操作
patients at high risk of OSAS using the Berlin Questionnaire to detect potential high risk of adverse respiratory
null
期刊论文
A pilot study on Paxlovid therapy for hemodialysis patients with severe acute respiratory syndrome coronavirus
期刊论文
Middle East respiratory syndrome coronavirus: current situation and travel-associated concerns
null
期刊论文
Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia
Sarah H. Alfaraj, Jaffar A. Al-Tawfiq, Talal A. Altuwaijri, Ziad A. Memish
期刊论文
Early and marked up-regulation of TNF-α in acute respiratory distress syndrome after cardiopulmonary
null
期刊论文
Cultural differences define diagnosis and genomic medicine practice: implications for undiagnosed diseases
null
期刊论文
Diagnosis and therapy of lacrimal system diseases by micro lacrimal endoscope
Nan XIANG, Weikun HU, Jing YUAN, Guigang LI, Haixia LIU
期刊论文
Characterization of polyclonal antibodies against nonstructural protein 9 from the porcine reproductive and respiratory
Mengmeng ZHAO,Juanjuan QIAN,Jiexiong XIE,Tiantian CUI,Songling FENG,Guoqiang WANG,Ruining WANG,Guihong ZHANG
期刊论文